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| In Brief 2001 Budget Request Scientific Priorities for Cancer Research Infrastructure Needed for Cancer Research How We Work Other Ways to Get This Information Cancer Information for Patients and Health Professionals |
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Learn More AboutThe Path to a New Cancer DrugThe pathway to the development of a new treatment or preventive drug begins at the cell. All cells have unique signatures composed of all the genes that are active, proteins that are secreted, processes that are followed, and pathways that are present. A cancer cell's signature differs from that of a normal cell; different genes are active or inactive, for example, or different pathways may be present. Certain components of a cancer cell's signature - genes, pathways, or patterns of behavior - may be especially vulnerable to the action of treatment or preventive agents. These components are the molecular targets at which treatments or preventives can be aimed.
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